Our lab contributed a chapter to the Second Edition of “Poly(ADP-Ribose) Polymerase: Methods and Protocols”, edited by Alexei V. Tulin. Check out how automated microscopy can be used for cell cycle resolved measurements of poly(ADP-ribose) formation.
Read how the DNA damage response utilizes replication-coupled dilution of a histone mark, H4K20me2, to guide BRCA1’s antagonist 53BP1 to pre-replicative chromatin and thereby facilitate the choice between NHEJ and HR during S-phase progression.
Motivated applications from postdoctoral researchers with a strong interest in genome stability or chromatin biology and willing to apply for fellowships are always encouraged. PhD students are recruited through the Life Science Zurich Graduate School.
Current Research Highlights
