As part of an active scientific community that studies the DNA damage response (DDR) and its impact on cancer and aging, research in the lab of Matthias Altmeyer is aimed at elucidating cellular mechanisms of genome integrity maintenance and their deregulation in human disease. Here you can explore who we are and what we do. Welcome!

Mini-Review published in Frontiers in Genetics

ERC grant awarded to the lab (ERC-2016-StG)

As part of the Horizon 2020 Research Program of the European Union an ERC Starting Grant was awarded to the lab. Open positions for ERC funded projects in our research program will be announced soon. We are extremely grateful for this encouraging support by the European Union.

Additional News

Mini-Review published in Frontiers in Genetics

Mini-Review published in Frontiers in Genetics

We contributed a mini-review to a Frontiers in Genetics research topic dedicated to “Ubiquitin and Ubiquitin-relative SUMO in DNA damage response”. Our article on “Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress” is now online.

Prior Publications

Postdoctoral researchers and PhD students

Postdoctoral researchers and PhD students

Motivated applications from postdoctoral candidates with a strong track record and willing to apply for fellowships are always encouraged. PhD students are recruited through the Molecular Life Sciences and Cancer Biology Programs of the Life Science Zurich Graduate School.

Current Openings

Current Research Highlights
Replication fork protection as a new mechanism of cancer therapy resistance
Cryo-EM reveals how the genome caretaker protein 53BP1 recognizes damaged chromatin

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